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Human CX3CR1 Validated Stable Cell Line-CHO
CX3CR1 is a GPCR expressed on natural killer cells, cytotoxic T lymphocytes, and macrophages. The sole ligand for CX3CR1, fractalkine, is an unusual chemokine that is expressed as a transmembrane molecule with a CX3C domain and a mucin domain. Fractalkine is highly expressed on endothelial cells activated by TNFalpha and other proinflammatory cytokines, and fractalkine/CX3CR1 interactions mediate recruitment of macrophages into the atherosclerotic plaque. In addition, fractalkine and CX3CR1 have been implicated in the pathogenesis of glomerulonephritis, HIV infection and rheumatoid arthritis.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1144 |
| Gene Name: | CX3CR1 |
| Abbr | CHO-HuCX3CR1 Validated |
| Alias | CX3CR1,CMKBRL1,GPR13,CCRL1,CMKDR1,V28,CMK-BRL1,CMK-BRL-1,C-X3-C CKR-1,GPR13,GPRV28,CMKBRL1 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | CX3CR1,CMKBRL1,GPR13,CCRL1,CMKDR1,V28,CMK-BRL1,CMK-BRL-1,C-X3-C CKR-1,GPR13,GPRV28,CMKBRL1 |
| Shipping | Dry ice |
| Species | Human |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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