CXCR2 (high affinity interleukin-8 receptor B, IL8RB) is a receptor to interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This receptor also binds to GRO/MGSA and NAP-2 with high affinity. Some highly potent small molecule antagonists of CXCR2 showed success in blocking in vivo trafficking of neutrophils, suggesting that antagonism of IL-8 at the receptor level is a viable therapeutic strategy in conditions such as pulmonary disease.

Product Information
Catalog #:	ACC-RG0220
Gene Name	CXCR2
Abbr	HEK293T-HuCXCR2-FLAG
Alias	CXCR2,IL8RB,CD182,CMKAR2,CXC-R2,CXCR-2,IL-8R B,IL8R2,IL8RA,IL8RB,CDw128b
Growth Properties	Adherent
Host Cell	HEK293T
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CXCR2,IL8RB,CD182,CMKAR2,CXC-R2,CXCR-2,IL-8R B,IL8R2,IL8RA,IL8RB,CDw128b

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