CXCR2 is a 7-TM G-protein coupled receptor that binds to the chemokines GROalpha, GRObeta, GROgamma, IL-8, ENA-78, NAP-2 and GCP-2. Neutrophils, mast cells and microvascular endothelial cells express CXCR2, and interactions of CXCR2 with its ligands promotes chemotaxis of these cell types. Studies with mice lacking CXCR2 indicate that CXCR2 promotes growth of primary tumors and secondary metastases, and plays an essential role in hyperoxia-induced lung injury. In addition, cytomegalovirus encodes a CXCR2-binding chemokine, vCXC-1, that promotes neutrophil migration to infected cells.

Product Information
Catalog #:	ACC-RG1145
Gene Name	CXCR2
Abbr	CHO-HuCXCR2 Validated
Alias	CXCR2,IL8RB,CD182,CMKAR2,CXC-R2,CXCR-2,IL-8R B,IL8R2,IL8RA,IL8RB,CDw128b
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CXCR2,IL8RB,CD182,CMKAR2,CXC-R2,CXCR-2,IL-8R B,IL8R2,IL8RA,IL8RB,CDw128b

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