CysLTR1 (Cysteinyl leukotriene receptor 1) is also known as LTD4 receptor (leukotriene D4 receptor), HG55 or HMTMF81. It is a receptor for cysteinyl leukotrienes and has highest affinity to leukotriene D4 (LTD4). The receptor mediates contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung caused by LTD4. Several antagonists, such as montelukast (Singulair), zafirlukast (Accolate) and pranlukast (Onon), are used in the treatment of asthma.
Product Information | |
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Catalog #: | ACC-RG0281 |
Gene Name | CYSLTR1 |
Abbr | HEK293T-HuCYSLTR1-FLAG |
Alias | CYSLTR1,CysLT(1),CysLT1,CYSLT1R,HG55,CYSLT1,CYSLTR,HMTMF81 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | CYSLTR1,CysLT(1),CysLT1,CYSLT1R,HG55,CYSLT1,CYSLTR,HMTMF81 |
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