The cysteinyl leukotrienes, leukotriene C4, leukotriene D4 and leukotriene E4, are arachidonic acid derivatives modified by glutathione, Cys-Gly or Cys. Activated mast cells release cysteinyl leukotrienes, which cause smooth muscle contraction, airway constriction, and vascular permeability. The biological effects of the cysteinyl leukotrienes are mediated by two GPCRs, CysLT1 and CysLT2. A CysLT1 selective antagonist, montelukast, is used clinically in the treatment of asthma.

Product Information
Catalog #:	ACC-RG1172
Gene Name	CYSLTR1
Abbr	CHO-HuCYSLTR1 Validated
Alias	CYSLTR1,CysLT(1),CysLT1,CYSLT1R,HG55,CYSLT1,CYSLTR,HMTMF81
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CYSLTR1,CysLT(1),CysLT1,CYSLT1R,HG55,CYSLT1,CYSLTR,HMTMF81

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