This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Product Information | |
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Catalog #: | ACC-RG1152 |
Gene Name | DRD3 |
Abbr | CHO-HuDRD3 Validated |
Alias | DRD3,D3DR,ETM1,FET1 |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | DRD3,D3DR,ETM1,FET1 |
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Catalog | Product Name | Gene Name | Species | Morphology | Price |
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ACC-RG0037 | HumanDRD3-tGFP Stable Cell Line-SHSY5Y | DRD3 | Human | Epithelial | INQUIRY |
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