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Human EDNRA Stable Cell Line-CHO
Endothelins are a family of vasoactive peptides that include ET-1, ET-2 and ET-3. To date, two subtype of endothelin receptors have been identified from mammalian cells, EDNRA (ETA) and EDNRB (ETB). The EDNRA receptors (ETA) have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The vasoconstrictor and proliferative effects of ET-1 are primarily mediated by the EDNRA receptor. This makes EDNRA a good target for drug development in a number of cardiovascular diseases, including congestive heart failure, hypertension, stroke, kidney failure, and a variety of non-cardiovascular conditions, such as asthma, chronic obstructive pulmonary disease, pain and cancer.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0838 |
| Gene Name: | EDNRA |
| Abbr | CHO-HuEDNRA |
| Alias | EDNRA,ETA,ET-A,ETAR,ETRA,ETA-R,hET-AR |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | EDNRA,ETA,ET-A,ETAR,ETRA,ETA-R,hET-AR |
| Shipping | Dry ice |
| Species | Human |
| Stability | 12 passages of continuous culture (6 weeks) at 2 passages/week |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1729 | Rat EDNRA Stable Cell Line-CHO-K1 | EDNRA | Rat | INQUIRY |
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