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Human F2RL1 Stable Cell Line-CHO
Protease-activated receptor-2 (PAR2) belongs to a four-member family of GPCRs that are activated by proteases (see Ossovskaya et al for review). These proteases cleave a specific extracellular amino-terminal domain of the receptor to reveal a tethered ligand, which in turn activates the receptor which couples via Gq to release intracellular calcium (Nystedt, S. et al., 1995). PAR2 is expressed in the vasculature, GI tract, CNS, lung, kidney, liver, and heart. PAR2 is a relevant target for arthritis, inflammation, bowel disease, and cancer.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0920 |
| Gene Name: | F2RL1 |
| Abbr | CHO-HuF2RL1 |
| Alias | F2RL1,GPR11,PAR2,PAR-2 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | F2RL1,GPR11,PAR2,PAR-2 |
| Shipping | Dry ice |
| Species | Human |
| Stability | 12 passages (6 weeks of continuous culture) |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1704 | Human F2RL1 Stable Cell Line-CHO-K1/Gα15 | F2RL1 | Human | INQUIRY | |
| ACC-RG1745 | Human F2RL1 Stable Cell Line-HeLa | F2RL1 | Human | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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