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Human GABRA4 Stable Cell Line-HEK293

Gamma-aminobutyric acid (GABA)-gated ion channels are widely distributed in the mammalian brain and are major mediators of inhibitory synaptic transmission. A typical GABA ion channel has a pentameric structure consisting of 5 protein subunits, often alpha, beta and gamma or delta, combining to form a central ion conducting pore across the cell membrane. In humans there are six genes that encode alpha subunits, three that encode beta, three that encode gamma, and an additional seven genes that encode other subunits whose function is less-well understood than the alpha, beta and gamma subunits. GABA ion channels open and close in response to secretion of GABA from presynaptic terminals. GABAA alpha4 channels comprised of alpha4, beta3, and gamma2 subunits are extrasynaptic, estimated to represent.

Product Information
Catalog #:  ACC-RI0007
Gene Name GABRA4
Abbr HEK293-HuGABRA4
Alias GABRA4,alpha 4
Growth Properties Adherent
Host Cell HEK293
Morphology Epithelial
Shipping Dry ice
Product Type Ion Channel Expressing Cell
Channel Type Chloride Channel
Channel Subgroup GABAa Receptor
Species Human
Product Format frozen
searchKeyword GABRA4,alpha 4
Our products are only for research use. Not intended for any clinical or diagnostic use.

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