Glucagon is a 29-amino acid peptide that stimulates glycogenolysis and gluconeogenesis in the liver to increase blood glucose. The receptor for glucagon is a class 2 (or class B) GPCR that signals through Gs to stimulate cAMP production. Mice lacking the glucagon receptor have mild hypoglycemia after fasting, and exhibit hyperplasia of pancreatic alpha-cells. Because of its role in promoting hyperglycemia, the glucagon receptor presents a potential target for treatment of diabetes.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1164 |
| Gene Name: | GCGR |
| Abbr | 1321N1-HuGCGR Validated |
| Alias | GCGR,GGR,GL-R,FLJ97182,MGC138246 |
| Growth Properties | Adherent |
| Host Cell | 1321N1 |
| Morphology | Glial |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | GCGR,GGR,GL-R,FLJ97182,MGC138246 |
| Shipping | Dry ice |
| Species | Human |
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