Glucagon is a 29-amino acid peptide that stimulates glycogenolysis and gluconeogenesis in the liver to increase blood glucose. The receptor for glucagon is a class 2 (or class B) GPCR that signals through Gs to stimulate cAMP production. Mice lacking the glucagon receptor have mild hypoglycemia after fasting, and exhibit hyperplasia of pancreatic alpha-cells. Because of its role in promoting hyperglycemia, the glucagon receptor presents a potential target for treatment of diabetes.
Product Information | |
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Catalog #: | ACC-RG1164 |
Gene Name | GCGR |
Abbr | 1321N1-HuGCGR Validated |
Alias | GCGR,GGR,GL-R,FLJ97182,MGC138246 |
Growth Properties | Adherent |
Host Cell | 1321N1 |
Morphology | Glial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GCGR,GGR,GL-R,FLJ97182,MGC138246 |
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