This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Product Information
Catalog #:	ACC-RG1650
Gene Name	GPBAR1
Host Cell	CHO-K1
Shipping	Dry Ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	GPBAR1

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