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Human GPR119 Stable Cell Line-CHO

GPR119 is expressed in insulin-producing beta cells where it modulates insulin release, thus making it a very attractive therapeutic target for metabolic disorders. GPR119 is activated by oleoylethanolamide (OEA) and by a novel selective small-molecule (PSN632408) which, when administered to high-fat-fed rats, suppresses food intake and reduces body weight gain. Another small molecule full-agonist (AR231453) enhances glucose-dependent insulin release, and improves oral glucose tolerance in wild-type mice, but not in GPR119 knock-out mice.

Product Information
Catalog #:  ACC-RG0855
Gene Name:  GPR119
Abbr CHO-HuGPR119
Alias GPR119,GPCR2,hGPCR2,MGC119957
Growth Properties Adherent
Host Cell CHO-K1
Morphology Epithelial-like
Product Format frozen
Product Type GPCR Expressing Cell
searchKeyword GPR119,GPCR2,hGPCR2,MGC119957
Shipping Dry ice
Species Human
Stability 12 passages
Our products are only for research use. Not intended for any clinical or diagnostic use.

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