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- Human GPR119 Stable Cell Line-CHO
Human GPR119 Stable Cell Line-CHO
GPR119 is expressed in insulin-producing beta cells where it modulates insulin release, thus making it a very attractive therapeutic target for metabolic disorders. GPR119 is activated by oleoylethanolamide (OEA) and by a novel selective small-molecule (PSN632408) which, when administered to high-fat-fed rats, suppresses food intake and reduces body weight gain. Another small molecule full-agonist (AR231453) enhances glucose-dependent insulin release, and improves oral glucose tolerance in wild-type mice, but not in GPR119 knock-out mice.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0855 |
| Gene Name | GPR119 |
| Abbr | CHO-HuGPR119 |
| Alias | GPR119,GPCR2,hGPCR2,MGC119957 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Stability | 12 passages |
| Product Format | frozen |
| searchKeyword | GPR119,GPCR2,hGPCR2,MGC119957 |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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