The orexins (orexina-A and orexin-b) have a range of physiological functions including the control of feeding and energy metabolism, modulation of neuroendocrine function, and regulation of the sleep-wake cycle. The two orexin receptor subtypes OX1 and OX2 both mediate the action of orexin-A and orexin-B and couple efficiently through Gq/11 to activate phospholipase C and lead to elevation of intracellular calcium, though orexin-A is equipotent at OX1 and OX2, whilst orexin-B displays a moderate selectivity for OX2.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0909 |
| Gene Name: | HCRTR2 |
| Abbr | CHO-HuHCRTR2 |
| Alias | HCRTR2,OX2R,ox2-R,ox-2-R |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | HCRTR2,OX2R,ox2-R,ox-2-R |
| Shipping | Dry ice |
| Species | Human |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1199 | Human HCRTR2-like Validated Stable Cell Line-CHO | HCRTR2 | Human | Epithelial-like | INQUIRY |
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