Histamine is one of the most studied biomolecules in medicine and is most notably known for its effects on smooth muscle contraction, vascular permeability and regulation of stomach acid. The histamine receptor H4 has been shown to have a role in chemotaxis and mediator release in a variety of immune cells, such as mast cells, eosinophils, dendritic cells, and T cells. The development of potent H4 receptor antagonists has great potential to open up the pathway for new therapeutic treatments in chronic inflammatory diseases, such as bronchial asthma, allergic gastrointestinal disease, and atopic dermatitis.
Product Information | |
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Catalog #: | ACC-RG1169 |
Gene Name | HRH4 |
Abbr | CHO-HuHRH4 Validated |
Alias | HRH4,AXOR35,GPCR105,GPRv53,H4R,HH4R,SP9144,H4,BG26 |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | HRH4,AXOR35,GPCR105,GPRv53,H4R,HH4R,SP9144,H4,BG26 |
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