Kv1.3 is widely expressed throughout the CNS and in organs/cells involved with immune system such as spleen, tonsils, T-lymphocytes, B-lymphocytes and macrophages. Kv1.3 is involved in the regulation of the resting membrane potential and calcium signalling in lymphocytes and oligodendrocytes. This ion channel is a target for immunosuppressants and Kv1.3 inhibitors have been proven effective treatment in slowing the progression of multiple sclerosis.
|Product Type||Ion Channel Expressing Cell|
|Channel Type||Potassium Channel|
|Channel Subgroup||Voltage-gated (Kv)|
|Catalog||Product Name||Gene Name||Species||Morphology||Price|
|ACC-RI0125||Human KCNA3 Stable Cell Line-HEK293||KCNA3||Human||Epithelial||INQUIRY|