Human KCNA5 Stable Cell Line-CHO

Kv1.5 is expressed in the brain (hippocampus, pituitary, microglia, oligodendrocytes and Schwann cells) as well as kidney, colon, aorta, pulmonary artery and smooth muscle. This ion channel is involved in the maintenance of the resting membrane potential and therefore regulates the activity electrically excitable cells. Kv1.5 is potentially a target for the management of atrial fibrillation. Since they are not found in the ventricles, drugs selective for this channel may be beneficial in the treatment of atrial fibrillation without the risk of causing ventricular arrhythmias. Apart from these instances where the purpose is to develop a cardiovascular drug targeted to Kv1.5, an interaction of lead development compounds with this channel is best avoided. This is due to the fact that the channel has such a widespread distribution and controls membrane excitability.

Product Information
Catalog #:	ACC-RI0030
Gene Name	KCNA5
Abbr	CHO-HuKCNA5
Alias	KCNA5,HK2,HPCN1,Kv1.5,HCK1,PCN1,ATFB7,KV1.5,MGC117058,MGC117059
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	Ion Channel Expressing Cell
Channel Type	Potassium Channel
Channel Subgroup	Voltage-gated (Kv)
Species	Human
Product Format	frozen
searchKeyword	KCNA5,HK2,HPCN1,Kv1.5,HCK1,PCN1,ATFB7,KV1.5,MGC117058,MGC117059