- Home
-
Screening
- Ionic Screening Service
-
Ionic Screening Panel
- Sodium Channels
- Potassium Channels
- Chloride Channels
- Calcium Channels
- TRP Channels
- ATP gated P2X Channels
- ASICs
- Nicotinic Acetylcholine Receptors
- Ionotropic Glutamate-gated Receptors
- GABAa Receptors
- Glycine Receptors
- 5-HT Receptors3
- Cystic Fibrosis Transmembrane Conductance Regulators (CFTR)
- Other Ion Channels
- Stable Cell Lines
- Cardiology
- Neurology
- Ophthalmology
-
Platform
-
Experiment Systems
- Xenopus Oocyte Screening Model
- Acute Isolated Cardiomyocytes
- Acute Dissociated Neurons
- Primary Cultured Neurons
- Cultured Neuronal Cell Lines
- iPSC-derived Cardiomyocytes/Neurons
- Acute/Cultured Organotypic Brain Slices
- Oxygen Glucose Deprivation Model
- 3D Cell Culture
- iPSC-derived Neurons
- Isolation and culture of neural stem/progenitor cells
- Animal Models
- Techinques
- Resource
- Equipment
-
Experiment Systems
- Order
- Careers
- Home
- Products
- Ionic Screening Panel
- Human KCNC1 Stable Cell Line-CHO
Human KCNC1 Stable Cell Line-CHO
Kv3.1 mRNA is abundantly expressed in auditory brain stem neurons that are able to spike at high frequencies. It has a high threshold of activation and rapid activation/deactivation kinetics. Evidence for functional Kv3.1 activity in such neurons can be derived from the rapidly activating and deactivating potassium currents seen here, that activate at a high-voltage threshold similar to that of heterologously expressed Kv3.1. There are indications that the phosphorylation state in rat Kv3.1 may play a part in the ability of auditory neurons to adjust to the ambient acoustic environment. It is thought that Kv3.1 subunits are likely to form homomultimers in lymphocytes and therefore could be a target for the development of novel immunosuppresants.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0037 |
| Gene Name | KCNC1 |
| Abbr | CHO-HuKCNC1 |
| Alias | KCNC1,Kv3.1,KV4,NGK2,KV3.1, |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Shipping | Dry ice |
| Product Type | Ion Channel Expressing Cell |
| Channel Type | Potassium Channel |
| Channel Subgroup | Voltage-gated (Kv) |
| Species | Human |
| Product Format | frozen |
| searchKeyword | KCNC1,Kv3.1,KV4,NGK2,KV3.1, |
Inquiry