Kv3.3 are voltage-gated, fast inactivating Shaw channels which play an important role in regulating neuronal output by modulating the delay and frequency of high frequency neuronal firing. They are highly expressed in areas of the brain involved with motor control such as the cerebellum. They have also been shown be expressed at the mammalian neuromuscular junction where they are thought to regulate transmitter release.
|Product Type||Ion Channel Expressing Cell|
|Channel Type||Potassium Channel|
|Channel Subgroup||Voltage-gated (Kv)|