The human KCNJ3 and KCNJ5 genes encode the pore-forming subunits of heteromeric Kir3.1/Kir3.4, an inward rectifier potassium channel. Kir3.1/Kir3.4 channels expressed in heart are linked to M2 muscarinic acetylcholine receptors that mediate vagal inhibitory control of heart rate. Kir3.1/Kir3.4 is a potential target for treatment of atrial fibrillation.
Product Information | |
---|---|
Catalog #: | ACC-RI0119 |
Gene Name | KCNJ5 |
Abbr | HEK293-HuKCNJ3/KCNJ5 |
Alias | KCNJ5,CIR,GIRK4,KATP1,Kir3.4,IRK-4,LQT13,KIR3.4 |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | Ion Channel Expressing Cell |
Channel Type | Potassium Channel |
Channel Subgroup | Inwardly rectifying (Kir) |
Species | Human |
Product Format | frozen |
searchKeyword | KCNJ5,CIR,GIRK4,KATP1,Kir3.4,IRK-4,LQT13,KIR3.4 |
Inquiry