The human KCNN4 gene encodes the pore-forming subunit of KCa3.1, the calcium-activated IK potassium channel. KCa3.1 channels expressed in lymphocytes, fibroblasts, proliferating vascular smooth muscle cells, vascular endothelium and, intestinal and airway epithelia are therapeutic targets in inflammatory diseases in these tissues. KCa3.1 channels expressed in erthrocytes have been investigated as targets for treatment of sickle cell anemia.
Product Information | |
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Catalog #: | ACC-RI0112 |
Gene Name: | KCNN4 |
Abbr | CHO-HuKCNN4 |
Alias | KCNN4,hIKCa1,hKCa4,hSK4,KCa3.1,SKCa4,SKCa 4,IK1,SK4,KCA4,IKCA1 |
Channel Subgroup | Calcium-activated (KCa) |
Channel Type | Potassium Channel |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Product Format | frozen |
Product Type | Ion Channel Expressing Cell |
searchKeyword | KCNN4,hIKCa1,hKCa4,hSK4,KCa3.1,SKCa4,SKCa 4,IK1,SK4,KCA4,IKCA1 |
Shipping | Dry ice |
Species | Human |
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