Kv7.2 and Kv7.3 are both voltage-gated, delayed rectifier potassium channels. Together they co assemble to form the M current in the brain. The M current is a slowly activating and deactivating potassium conductance that plays a crucial role in determining the excitability of neurons as well as their responsiveness to synaptic inputs. This current is also expressed in many neurons in the central nervous system. Enhancers of the M current are used for antiepileptic therapy and blockers have been shown to enhance learning and memory.
|Product Type||Ion Channel Expressing Cell|
|Channel Type||Potassium Channel|
|Channel Subgroup||Voltage-gated (Kv)|