The human KCNQ2 and KCNQ3 genes encode the pore-forming subunits of Kv7.2 and Kv7.3, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive neuronal activity. Mutations in KCNQ2 or KCNQ3 that reduce M-current amplitude are responsible for some forms of benign familial neonatal seizure. Kv7.2/Kv7.3 channels are therapeutic targets in seizure, stroke, migraine, dementia, bipolar disorder, anxiety, and neuropathic pain.
Product Information | |
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Catalog #: | ACC-RI0145 |
Gene Name | KCNQ3 |
Abbr | HEK293-HuKCNQ2/KCNQ3 |
Alias | KCNQ3,EBN2,Kv7.3,BFNC2,KV7.3,FLJ37386,FLJ38392,DKFZp686C0248 |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | Ion Channel Expressing Cell |
Channel Type | Potassium Channel |
Channel Subgroup | Voltage-gated (Kv) |
Species | Human |
Product Format | frozen |
searchKeyword | KCNQ3,EBN2,Kv7.3,BFNC2,KV7.3,FLJ37386,FLJ38392,DKFZp686C0248 |
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