The human KCNQ3 and KCNQ5 genes encode the pore-forming subunits of Kv7.3 and Kv7.5, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive activity in neurons. Mutations in KCNQ3 that reduce M-current are responsible for some forms of benign familial neonatal seizure. Kv7.3/Kv7.5 channels expressed in neurons are therapeutic targets in seizure and cognitive impairment.
Product Information | |
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Catalog #: | ACC-RI0147 |
Gene Name | KCNQ5 |
Abbr | HEK293-HuKCNQ3/KCNQ5 |
Alias | KCNQ5,Kv7.5 |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | Ion Channel Expressing Cell |
Channel Type | Potassium Channel |
Channel Subgroup | Voltage-gated (Kv) |
Species | Human |
Product Format | frozen |
searchKeyword | KCNQ5,Kv7.5 |
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