The human KCNQ3 and KCNQ5 genes encode the pore-forming subunits of Kv7.3 and Kv7.5, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive activity in neurons. Mutations in KCNQ3 that reduce M-current are responsible for some forms of benign familial neonatal seizure. Kv7.3/Kv7.5 channels expressed in neurons are therapeutic targets in seizure and cognitive impairment.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0147 |
| Gene Name: | KCNQ5 |
| Abbr | HEK293-HuKCNQ3/KCNQ5 |
| Alias | KCNQ5,Kv7.5 |
| Channel Subgroup | Voltage-gated (Kv) |
| Channel Type | Potassium Channel |
| Growth Properties | Adherent |
| Host Cell | HEK293 |
| Morphology | Epithelial |
| Product Format | frozen |
| Product Type | Ion Channel Expressing Cell |
| searchKeyword | KCNQ5,Kv7.5 |
| Shipping | Dry ice |
| Species | Human |
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