Human LPAR1 Stable Cell Line-RH7777

Lysophosphatidic acid (LPA) is a small, bioactive phospholipid that mediates multiple cellular responses, including proliferation, differentiation, motility, and survival in both normal physiology and disease. The extracellular actions of LPA are mediated primarily through its interaction with five G protein-coupled receptors which include LPA1(EDG2), LPA2(EDG4), LPA3(EDG7), LPA4 (GPR23 or P2Y9) and LPA5 (GPR92). Among them, LPA1 (EDG2) is most widely expressed in normal tissue during growth and development. After LPA stimulation, LPA1 (EDG2) couples to Gi and G12/13 and was reported to play an important role in development of chronic neuroimmune disease and initiation of neuropathic pain.

Product Information
Catalog #:	ACC-RG0870
Gene Name	LPAR1
Abbr	RH7777-HuLPAR1
Alias	LPAR1,EDG2,edg 2,Gpcr26,GPR26,LPA1,Mrec1.3,rec.1.3,vzg 1,LPA-1,EDG2,VZG1,edg-2,vzg-1
Growth Properties	Loosely adherent
Host Cell	RH7777
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Stability	12 passages of continuous culture (6 weeks) at 2 passages/week
Product Format	frozen
searchKeyword	LPAR1,EDG2,edg 2,Gpcr26,GPR26,LPA1,Mrec1.3,rec.1.3,vzg 1,LPA-1,EDG2,VZG1,edg-2,vzg-1