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- Human MCHR1 Validated Stable Cell Line-CHO
Human MCHR1 Validated Stable Cell Line-CHO
Melanin-concentrating hormone (MCH) is a cyclic, 19 amino acid peptide produced in the lateral hypothalamus and other regions of the mammalian brain. When administered intracerebrally or overexpressed transgenically in rodents, MCH stimulates food intake and weight gain. A receptor for MCH, previously identified as an orphan receptor SLC-1 and renamed MCHR1, has been identified in humans and rodents. Consistent with a role in hypothalmic control of feeding behavior, MCHR1 is expressed in in the ventromedial and dorsomedial nuclei of the hypothalamus. Genetic ablation and pharmacological antagonism of MCHR1 in rodents results in resistance to obesity caused by a high fat diet or leptin deficiency. Thus, MCHR1 is an attractive target for obesity.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1173 |
| Gene Name | MCHR1 |
| Abbr | CHO-HuMCHR1 Validated |
| Alias | MCHR1,GPR24,MCH1R,SLC1,SLC-1,MCH-1R,MGC32129 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Product Format | frozen |
| searchKeyword | MCHR1,GPR24,MCH1R,SLC1,SLC-1,MCH-1R,MGC32129 |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1636 | Human MCHR1 Stable Cell Line-HEK293 | MCHR1 | Human | INQUIRY | |
| ACC-RG0296 | Human MCHR2 Stable Cell Line-CHO dhfr- | MCHR1 | Human | Epithelial-like | INQUIRY |
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