P2Y1 is a GPCR that binds to ADP and ATP to activate Gq. A wide variety of cells and tissues express P2Y1. Vascular endothelium and smooth muscle express P2Y1, and mediate vascular tone both in the resting state and in thrombosis, when platelet-derived ATP and ADP are present at high concentrations. In addition, activation of P2Y1 expressed on platelets leads to ADP-induced shape changes and aggregation.
Product Information | |
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Catalog #: | ACC-RG0718 |
Gene Name | P2RY1 |
Abbr | 1321N1-HuP2RY1/Galpha15 |
Alias | P2RY1,P2Y1 |
Growth Properties | Adherent |
Host Cell | 1321N1 |
Morphology | Glial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | P2RY1,P2Y1 |
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