Peroxisome Proliferator-Activated Receptor-gamma (PPAR gamma) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with retinoic acid-like receptor (RXR). It is involved in the regulation of glucose and lipid metabolism. Agonists include the class of anti-diabetic agents called thiazolidinediones (TZD) or "glitazones." Rosiglitazone (Avandia) and Pioglitazone (Actos) are two PPAR gamma agonists currently marketed for treatment of type 2 diabetes. PPAR gamma agonists may also be therapeutically important in the treatment of coronary artery disease, obesity, and cancer.
|Abbr||HEK 293H(UAS-bla)-HuPPAR gamma(LBD)-GAL4(DBD)|
|Host Cell||HEK 293T|
|Product Type||GPCR Expressing Cell|