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Human PTGDR2 Validated Stable Cell Line-CHO
The chemoattractant-homologous receptor expressed on TH2 cells (CRTH2, also known as DP2 and GPR44) serves as a receptor for prostaglandin D2 (PGD2) and has been reported to mediate PGD2-dependent migration of eosinophils. DP2 mediates the pro-inflammatory effects of PGD2 generated in allergic inflammation. 11-Dehydrothromboxane B2 (11-dehydro-TXB2) was found to be a full agonist of the DP2 receptor and hence might cause the receptor activation in cellular contexts where PGD-synthase is not present. Antagonism of the 11-dehydro-TXB2/DP2 axis may be of therapeutic relevance.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1203 |
| Gene Name: | PTGDR2 |
| Abbr | CHO-HuPTGDR2 Validated |
| Alias | PTGDR2,GPR44,CD294,CRTH2,DP2,DL1R |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | PTGDR2,GPR44,CD294,CRTH2,DP2,DL1R |
| Shipping | Dry ice |
| Species | Human |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1701 | Human PTGDR2 Stable Cell Line-CHO-K1/Gα15 | PTGDR2 | Human | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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