S1P1 (or EDG1) is a widely distributed G-protein-coupled receptor for sphingosine-1-phosphate (S1P), a blood-borne bioactive lipid. Stimulation of the S1P1 receptor triggers a Gi-linked pathway, leading to growth, survival, migration, and morphogenesis. Disruption of the S1P1 gene in mice results in embryonic lethality because of its key role within endothelial cells in regulating the coverage of blood vessels by vascular smooth muscle cells. S1P1 also mediates activation of Rac and functions as a typical chemotactic receptor.

Product Information
Catalog #:	ACC-RG0289
Gene Name	S1PR1
Abbr	CHO-K1 Galphaqi5-HuS1PR1-FLAG
Alias	S1PR1,EDG1,CD363,D1S3362,edg 1,S1P1,ECGF1,EDG-1,CHEDG1,FLJ58121
Growth Properties	Adherent
Host Cell	CHO-K1 Galphaqi5
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	S1PR1,EDG1,CD363,D1S3362,edg 1,S1P1,ECGF1,EDG-1,CHEDG1,FLJ58121

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