Edg receptors constitute of family of 8 GPCRs (designated as Edg-1 through Edg-8) that can be further sub-classified as sphingosine 1-phosphate receptors (S-1-P) and lysophosphatidic acid (LPA) receptors. The Edg-1 receptor is an S-1-P receptor that is coupled to a variety of intracellular responses via Gi and Go. The Edg-1 receptor was initially cloned as an immediate-early gene induced during differentiation of human endothelial cells, an in vitro model of angiogenesis. It has been shown to play a critical role in regulating cellular proliferation and survival.
Product Information | |
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Catalog #: | ACC-RG0834 |
Gene Name | S1PR1 |
Abbr | CHO-HuS1PR1 |
Alias | S1PR1,EDG1,CD363,D1S3362,edg 1,S1P1,ECGF1,EDG-1,CHEDG1,FLJ58121 |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Stability | 6 passages |
Product Format | frozen |
searchKeyword | S1PR1,EDG1,CD363,D1S3362,edg 1,S1P1,ECGF1,EDG-1,CHEDG1,FLJ58121 |
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