TRP ion channels are regulated through signaling pathways that are activated by G-protein-coupled receptors and other membrane receptors. In sensory neurons, TRPV1 activity is regulated by a number of phospholipase C (PLC)–coupled receptors, including the B2 bradykinin receptor, TrkA, the receptor for nerve growth factor (NGF), and ATP receptors. Bradykinin and NGF sensitize TRPV1 to heat and to noxious chemical stimuli, leading to thermal hyperalgesia.
Product Information | |
---|---|
Catalog #: | ACC-RI0056 |
Abbr | HEK293-HuTRPA1 |
Alias | TRPA1,ANKTM1,ANKTM1 |
Channel Subgroup | TRPA (ankyrin) |
Channel Type | TRP Channel |
Gene Name | TRPA1 |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Product Format | frozen |
Product Type | Ion Channel Expressing Cell |
searchKeyword | TRPA1,ANKTM1,ANKTM1 |
Shipping | Dry ice |
Species | Human |
Related Products
Catalog | Product Name | Gene Name | Species | Morphology | Price |
---|---|---|---|---|---|
ACC-RI0191 | Human TRPA1 Stable Cell Line-CHO | TRPA1 | Human | Epithelial-like | INQUIRY |
ACC-RG1231 | Human TRPA1/Photina Stable Cell Line-HEK | TRPA1 | Human | Epithelial | INQUIRY |
Inquiry