Delta opioid receptor (DOR) inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. In rats, morphine tolerance is associated with DOR-mediated activation of cortical CCKergic systems. There are indications that some DOR antagonists produce potent antitussive effects and may be considered as candidates of antitussive drugs. In contrast, some DOR agonists have shown antinociceptive, seizuregenic and convulsive properties, implicating a role for the receptor in depression. Clinical experiments have demonstrated that exogenously administered delta opioid peptides had antidepressant activity, suggesting that the receptor may provide a new therapeutic target for treating depression.

Product Information
Catalog #:	ACC-RG0340
Gene Name	Oprd1
Abbr	CHO dhfr--RatOprd1
Alias	OPRD1,DOR-1,D-OR-1
Growth Properties	Adherent
Host Cell	CHO dhfr-
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Rat
Product Format	frozen
searchKeyword	OPRD1,DOR-1,D-OR-1

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