CCR9 (C-C chemokine receptor type 9) is a thymus-specific receptor for chemokine CCL25 (SCYA25 or TECK). It is an alternative co-receptor with CD4 for HIV-1 infection. Activation of the receptor may lead to potent cFLIP(L)-independent resistance to cycloheximide-induced apoptosis and modest resistance to Fas-mediated apoptosis possibly via activation of multiple signaling components involving Akt and glycogen synthase kinase 3beta. Thus, dissection of signaling components involved in the CCR9-mediated antiapoptosis could be a framework for cell survival mechanisms and may provide options for therapeutic interventions.

Product Information
Catalog #:	ACC-RG0210
Gene Name	CCR9
Abbr	HEK293T Galphaqi5-HuCCR9-FLAG
Alias	CCR9,GPR28,CDw199,GPR 9 6,GPR-9-6,CC-CKR-9
Growth Properties	Adherent
Host Cell	HEK293T Galphaqi5
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR9,GPR28,CDw199,GPR 9 6,GPR-9-6,CC-CKR-9

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