CCR9 (C-C chemokine receptor type 9) is a thymus-specific receptor for chemokine CCL25 (SCYA25 or TECK). It is an alternative co-receptor with CD4 for HIV-1 infection. Activation of the receptor may lead to potent cFLIP(L)-independent resistance to cycloheximide-induced apoptosis and modest resistance to Fas-mediated apoptosis possibly via activation of multiple signaling components involving Akt and glycogen synthase kinase 3beta. Thus, dissection of signaling components involved in the CCR9-mediated antiapoptosis could be a framework for cell survival mechanisms and may provide options for therapeutic interventions.
Product Information | |
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Catalog #: | ACC-RG0213 |
Gene Name | Ccr9 |
Abbr | HEK293T-MouseCcr9-FLAG |
Alias | CCR9,CCR-9,CC-CKR-9,Cmkbr10,GPR-9-6 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Mouse |
Product Format | frozen |
searchKeyword | CCR9,CCR-9,CC-CKR-9,Cmkbr10,GPR-9-6 |
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