Muscarinic acetylcholine receptors are G protein-coupled receptors. M1, M3, M5 receptors couple to G proteins of the Gq/11 family, which activate phospholipase C. M2 and M4 receptors couple to Gi/o-type G proteins that inhibit adenylyl cyclase activity. Muscarinic receptors control many effects of acetylcholine in the central and peripheral nervous system. M1 receptor is known to mediate slow EPSP at the ganglion in the postganglionic nerve, and it is also found in exocrine glands and in the CNS. M1 receptor is thought to be implicated in Alzheimer′s disease.

Product Information
Catalog #:	ACC-RG0005
Gene Name	CHRM1
Abbr	U2OS-HuCHRM1
Alias	CHRM1,HM1,M1,M1R
Growth Properties	Adherent
Host Cell	U2OS
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CHRM1,HM1,M1,M1R

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