The FDA, ICH S7B guidelines set out a non-clinical testing strategy to assess the effects of pharmaceuticals on ventricular repolarisation and proarrhythmic risk. The most common mechanism for this is inhibition of the delayed rectified potassium current IKr. The human ether-à-go-go-related gene (hERG) encodes the potassium ion channel responsible for IKr.
Product Information | |
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Catalog #: | ACC-RI0022 |
Gene Name | ERG |
Abbr | HEK293-HuERG |
Alias | ERG,erg 3,p55,erg-3, |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | Ion Channel Expressing Cell |
Channel Type | Potassium Channel |
Channel Subgroup | Ikr, Kv11.1 |
Species | Human |
Product Format | frozen |
searchKeyword | ERG,erg 3,p55,erg-3, |
Related Products
Catalog | Product Name | Gene Name | Species | Morphology | Price |
---|---|---|---|---|---|
ACC-RI0021 | Human ERG Stable Cell Line-CHO | ERG | Human | Epithelial-like | INQUIRY |
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