This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

Product Information
Catalog #:	ACC-RG1629
Gene Name	HTR2C
Host Cell	HEK293
Shipping	Dry Ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	HTR2C

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG0389	Human HTR2C-FLAG Stable Cell Line-CHO	HTR2C	Human	Epithelial-like	INQUIRY
ACC-RG0783	Human HTR2C Stable Cell Line-CHO	HTR2C	Human	Epithelial-like	INQUIRY
ACC-RG1104	Human HTR2C(edited) Validated Stable Cell Line-CHO	HTR2C	Human	Epithelial-like	INQUIRY
ACC-RG1105	Human HTR2C(not edited) Validated Stable Cell Line-1321N1	HTR2C	Human	Glial	INQUIRY