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Human KCNH2 Stable Cell Line-CHO
The human KCNH2 gene encodes the pore-forming subunit of Kv11.1, the voltage-gated hERG potassium channel. HERG channels are upregulated in some types of cancer and may serve as a tumor marker. KCNH2 mutations cause inherited forms of cardiac disorders including both long QT (loss-of-function) and short QT (gain-of-function) syndromes. Inhibition of HERG channels by pharmaceuticals is the primary cause of acquired long QT syndrome and drug-induced torsade de pointe. Therefore, HERG is an anti-target in cardiac risk assessment.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0136 |
| Gene Name: | KCNH2 |
| Abbr | CHO-HuKCNH2 |
| Alias | KCNH2,LQT2,erg1,HERG,Kv11.1,ERG-1,H-ERG,hERG-1,ERG1,SQT1,HERG1 |
| Channel Subgroup | Voltage-gated (Kv) |
| Channel Type | Potassium Channel |
| Growth Properties | Adherent |
| Host Cell | CHO |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | Ion Channel Expressing Cell |
| searchKeyword | KCNH2,LQT2,erg1,HERG,Kv11.1,ERG-1,H-ERG,hERG-1,ERG1,SQT1,HERG1 |
| Shipping | Dry ice |
| Species | Human |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RI0135 | Human KCNH2 Stable Cell Line-HEK293 | KCNH2 | Human | Epithelial | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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