The human KCNQ2 and KCNQ4 genes encode the pore-forming subunits of Kv7.2 and Kv7.4, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive activity in neurons. Mutations in KCNQ2 that reduce M-current are responsible for some forms of benign familial neonatal seizure. KCNQ4 loss-of-function mutations cause hereditary deafness. Kv7.2/Kv7.4 channels are therapeutic targets in seizure and neuropathic pain.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0146 |
| Gene Name: | KCNQ4 |
| Abbr | CHO-HuKCNQ2/KCNQ4 |
| Alias | KCNQ4,DFNA2,Kv7.4,KV7.4,DFNA2A |
| Channel Subgroup | Voltage-gated (Kv) |
| Channel Type | Potassium Channel |
| Growth Properties | Adherent |
| Host Cell | CHO |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | Ion Channel Expressing Cell |
| searchKeyword | KCNQ4,DFNA2,Kv7.4,KV7.4,DFNA2A |
| Shipping | Dry ice |
| Species | Human |
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| Catalog | Product Name | Gene Name | Species | Morphology | Price |
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| ACC-RI0045 | Human KCNQ4 Stable Cell Line-HEK293 | KCNQ4 | Human | Epithelial | INQUIRY |
| ACC-RI0148 | Human KCNQ4 Stable Cell Line-CHO | KCNQ4 | Human | Epithelial-like | INQUIRY |
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