Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptorfunction and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a highpotency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulationlocomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases inintracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that thisreceptor is G(q)-coupled.

Product Information
Catalog #:	ACC-RG1664
Gene Name	MRGPRX2
Host Cell	CHO-K1
Shipping	Dry Ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	MRGPRX2

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