This receptor belongs to a family of 4 sensory neuron-specific G-protein coupled receptors that are expressed in small diameter primary sensory neurons and in several other tissues. MrgX2 is a Gi- and Gq-coupled receptor which is potently activated by cortistatin-14. Because of its expression in sensory neurons and because these sensory neurons transmit pain sensation, this receptor is of interest as a therapeutic targets for pain medications. This cell line, expressed in HEK293 cells with no other exogenous G proteins, displays a robust calcium response and will be useful as a drug discovery reagent.
Product Information | |
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Catalog #: | ACC-RG0895 |
Gene Name | MRGPRX2 |
Abbr | HEK293-HuMRGPRX2 |
Alias | MRGPRX2,MRGX2 |
Growth Properties | Adherent |
Host Cell | HEK293 |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Stability | At least 8 passages |
Product Format | frozen |
searchKeyword | MRGPRX2,MRGX2 |
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