μ opioid receptor (MOR) is a G protein-coupled receptor for beta -endorphin. The receptor activation inhibits neurotransmitter release by reducing calcium currents and increasing potassium conductance. MOR mediates positive reinforcement following direct (morphine) or indirect (alcohol, cannabinoids, nicotine) activation. MOR plays a genetic role in the control of gut inflammation. MOR-deficient mice are highly susceptible to colon inflammation, with a 50% mortality rate occurring 3 days after administration of TNBS that induces inflammation. MOR agonists regulate cytokine production and T cell proliferation and might be new therapeutic molecules in inflammatory bowel disease.

Product Information
Catalog #:	ACC-RG0345
Gene Name	OPRM1
Abbr	CHO-HuOPRM1-FLAG
Alias	OPRM1,MOR1,MOP,hMOP,M-OR-1,MOR,LMOR,OPRM,KIAA0403
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	OPRM1,MOR1,MOP,hMOP,M-OR-1,MOR,LMOR,OPRM,KIAA0403

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