Mu opioid receptor (MOR) is a receptor for beta-endorphin, inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. MOR signaling and regulation are strongly agonist-dependent. MOR mediates positive reinforcement following direct (morphine) or indirect (alcohol, cannabinoids, nicotine) activation. MOR plays a genetic role in the control of gut inflammation. MOR-deficient mice are highly susceptible to colon inflammation, with a 50% mortality rate occurring 3 days after administration of TNBS that induces inflammation. MOR agonists regulate cytokine production and T cell proliferation and might be new therapeutic molecules in inflammatory bowel disease.

Product Information
Catalog #:	ACC-RG0344
Gene Name	Oprm1
Abbr	CHO dhfr--RatOprm1
Alias	OPRM1,MOR-1,MUOR1,M-OR-1,MORA,Oprm,Oprrm1
Growth Properties	Adherent
Host Cell	CHO dhfr-
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Rat
Product Format	frozen
searchKeyword	OPRM1,MOR-1,MUOR1,M-OR-1,MORA,Oprm,Oprrm1

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG1696	Human OPRM1 Stable Cell Line-CHO-K1/Gα15	OPRM1	Human		INQUIRY
ACC-RG1317	Human OPRM1/Apoaequorin Stable Cell Line-CHO	OPRM1	Human	Epithelial-like	INQUIRY
ACC-RG0345	Human OPRM1-FLAG Stable Cell Line-CHO	OPRM1	Human	Epithelial-like	INQUIRY
ACC-RG0896	Human OPRM1 Stable Cell Line-CHO	OPRM1	Human	Epithelial-like	INQUIRY
ACC-RG0052	Human OPRM1-SNAP Stable Cell Line-CHO	OPRM1	Human	Epithelial-like	INQUIRY