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Human SCN9A Stable Cell Line-HEK293

Nav1.7 is a voltage-gated sodium channel alpha subunit. It is expressed in all types of DRG neurons, sympathetic neurons, Schwann cells and neuroendocrine cells. This channel is involved in action potential initiation and transmission in peripheral neurons and is a potential target for local anaesthetic agents. Specific hereditary mutations in the gene encoding Nav1.7, SCN9A, result in the painful neuropathies, erythermalgia and paroxysmal extreme pain disorder, that can be ascribed to altered firing of pain sensing neurons. Changes in the expression levels of the channel correlates with increases in neuronal excitability in acute and chronic pain syndromes. Hence due to their relatively discrete location and fundamental role in mediating certain types of pain they may be promising targets for pharmacological intervention.

Product Information
Catalog #:  ACC-RI0053
Gene Name SCN9A
Abbr HEK293-HuSCN9A
Alias SCN9A,ETHA,Nav1.7,NE NA,NENA,PN1,hNE-Na,SFNP,FEB3B,NE-NA,GEFSP7
Growth Properties Adherent
Host Cell HEK293
Morphology Epithelial
Shipping Dry ice
Product Type Ion Channel Expressing Cell
Channel Type Sodium Channel
Species Human
Product Format frozen
searchKeyword SCN9A,ETHA,Nav1.7,NE NA,NENA,PN1,hNE-Na,SFNP,FEB3B,NE-NA,GEFSP7

Related Products

Catalog Product Name Gene Name Species Morphology Price
ACC-RI0170 Human SCN9A Stable Cell Line-CHO SCN9A Human Epithelial-like INQUIRY
Our products are only for research use. Not intended for any clinical or diagnostic use.

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