GPR120 is a G protein-coupled receptor for the long-chain free fatty acids. GPR120 mediated calcium mobilization, Erk1/Erk2 activation and GLP1 secretion. Unsaturated long-chain FFAs had a dose-dependent stimulatory effect, and alpha-linolenic acid was the most potent. GPR120 and GLP1 colocalized in human colonic intraepithelial neuroendocrine cells, and GPR120 may mediate dietary FFAstimulated GLP1 secretion.
Product Information | |
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Catalog #: | ACC-RG0247 |
Gene Name | O3far1 |
Abbr | HEK293T-RatO3far1-FLAG |
Alias | O3FAR1,Gpr120 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Rat |
Product Format | frozen |
searchKeyword | O3FAR1,Gpr120 |
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