P2RY12 or P2Y12 is a G-protein coupled receptor for ADP and ATP. ADT released from platelets acts in a positive feedback mechanism on P2Y12 and P2Y1 on platelets and is critical for sustained aggregation and stabilization of thrombin. P2Y12 receptor plays a central role in platelet activation and is the target of of antithrombotic drugs such as ticlopidine and clopidogrel.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0374 |
| Gene Name: | P2RY12 |
| Abbr | 1321N1-HuP2RY12 |
| Alias | P2RY12,HORK3,P2Y12,SP1999,ADPG-R,BDPLT8,P2T(AC),P2Y(AC),P2Y(ADP),P2Y(cyc) |
| Growth Properties | Adherent |
| Host Cell | 1321N1 |
| Morphology | Glial |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | P2RY12,HORK3,P2Y12,SP1999,ADPG-R,BDPLT8,P2T(AC),P2Y(AC),P2Y(ADP),P2Y(cyc) |
| Shipping | Dry ice |
| Species | Human |
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| ACC-RG0373 | Rat P2ry12 Stable Cell Line-CHO dhfr- | P2ry12 | Rat | Epithelial-like | INQUIRY |
| ACC-RG1208 | Human P2RY12 Validated Stable Cell Line-CHO | P2RY12 | Human | Epithelial-like | INQUIRY |
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