P2RY12 or P2Y12 is a G-protein coupled receptor for ADP and ATP. ADT released from platelets acts in a positive feedback mechanism on P2Y12 and P2Y1 on platelets and is critical for sustained aggregation and stabilization of thrombin. P2Y12 receptor plays a central role in platelet activation and is the target of of antithrombotic drugs such as ticlopidine and clopidogrel.
Product Information | |
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Catalog #: | ACC-RG0374 |
Gene Name | P2RY12 |
Abbr | 1321N1-HuP2RY12 |
Alias | P2RY12,HORK3,P2Y12,SP1999,ADPG-R,BDPLT8,P2T(AC),P2Y(AC),P2Y(ADP),P2Y(cyc) |
Growth Properties | Adherent |
Host Cell | 1321N1 |
Morphology | Glial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | P2RY12,HORK3,P2Y12,SP1999,ADPG-R,BDPLT8,P2T(AC),P2Y(AC),P2Y(ADP),P2Y(cyc) |
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