P2RY12 or P2Y12 is a G-protein coupled receptor for ADP and ATP. ADT released from platelets acts in a positive feedback mechanism on P2Y12 and P2Y1 on platelets and is critical for sustained aggregation and stabilization of thrombin. P2Y12 receptor plays a central role in platelet activation and is the target of of antithrombotic drugs such as ticlopidine and clopidogrel.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0373 |
| Gene Name: | P2ry12 |
| Abbr | CHO dhfr--RatP2ry12 |
| Alias | P2RY12,P2y12 |
| Growth Properties | Adherent |
| Host Cell | CHO dhfr- |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | P2RY12,P2y12 |
| Shipping | Dry ice |
| Species | Rat |
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| ACC-RG0374 | Human P2RY12 Stable Cell Line-1321N1 | P2RY12 | Human | Glial | INQUIRY |
| ACC-RG1208 | Human P2RY12 Validated Stable Cell Line-CHO | P2RY12 | Human | Epithelial-like | INQUIRY |
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