P2RY12 (Purinergic Receptor P2Y12) is a Protein Coding gene. Diseases associated with P2RY12 include Bleeding Disorder, Platelet-Type, 8 and Drug Metabolism, Poor, Cyp2c19-Related. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled adenosine receptor activity. An important paralog of this gene is P2RY13. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Product Information | |
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Catalog #: | ACC-RG1771 |
Gene Name | P2RY12 |
Abbr | P2RY12 |
Alias | P2RY12 |
Host Cell | 1321N1/Gα15 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | Liquid nitrogen |
searchKeyword | P2RY12 |
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