The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Information
Catalog #:	ACC-RG0048
Gene Name	EDNRB
Abbr	HEK293-HuEDNRB-SNAP
Alias	EDNRB,ET-B,ETBR,ETRB,HSCR,WS4A,BCDS,ET-BR,HSCR2
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	EDNRB,ET-B,ETBR,ETRB,HSCR,WS4A,BCDS,ET-BR,HSCR2

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