The endothelins and their receptors are referred as the endothelin (ET) axis and this axis has been implicated in diverse tumours.
Endothelin B receptor (ETB) may oppose cancer advance by helping apoptosis and clearing ET-1; however, it has recently been involved in the progress of some tumour as melanomas or oligodendrogliomas. The multigenic disorder, Hirschsprung disease type 2, is due to mutation in endothelin receptor type B gene.

Product Information
Catalog #:	ACC-RG0021
Gene Name	EDNRB
Abbr	U2OS-HuEDNRB
Alias	EDNRB,ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A
Growth Properties	Adherent
Host Cell	U2OS
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	EDNRB,ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A

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